Table 2 Asymptomatic shedding of HSV-1 detected by PCR from mouth swabs (saliva) of healthy subjects
Authors, Year | N | Individuals: total positive/total subjects | Shedding frequency: total positiveswabs/total swabs | Mouth swab frequency: numberof swabs/subject |
|---|---|---|---|---|
Robinson et al., 1992 [65] | 12 | 12/12 (100%) | 0/0 (0%) | 0 |
Robinson et al., 1992 [65] | 12* | 0/12 (0%) | 0/0 (0%) | 0 |
Tateishi et al., 1994 [63] | 1000 | 46/1000 (4.6%) | 46/1000 (4.6%) | one |
Kriesel et al., 1994 [66] | 27 | 3/27 (11%) | 3/27 (11%) | one |
Lee et al., 1996 [67] | 87 | 12/87 (13.8%) | 12/87 (13.8%) | one |
Knaup et al., 2000 [68] | 30 | 19/30 (63.3%) | 39/290 (13.5%) | 9-10 |
Druce et al., 2002 [69] | 477 | 43/477 (9%) | 43/477 (9%) | one |
Gleeson et al., 2002 [70] | 14 | 0/14 (0%) | 0/0 (0%) | 0 |
Youssef et al., 2002 [71] | 5 | 1/5 (20%) | 1/5 (20%) | one |
Miller et al., 2004 [72] | 123 | 11/123 (8.9%) | 11/123 (8.9%) | one |
Miller et al., 2004 [72] | 63** | 13/63 (21%) | 17/217 (7.8%) | 3-4 |
Kaufman et al., 2005 [73] | 50 | 46/50 (92%) | 1020/2712 (37.6%) | 54 |
Miller et al., 2005 [74] | 58 | 1/58 (1.7%) | 1/58 (1.7%) | one |
da Silva et al., 2005 [75] | 25 | 25/25 (100%) | 162/309(52.4%) | 12-13 |
Lin et al., 2005 [76] | 60 | 4/60 (6.7%) | 4/60 (6.7%) | one |
Kumar et al., 2009 [77] | 14***** | 12/14 (86%) | 357/840 (42%) | 60 |
Kumar et al., 2009 [77] | 15*** | 15/15 (100%) | 465/900 (52%) | 60 |
Kumar et al., 2009 [77] | 16**** | 15/16 (94%) | 701/961 (73%) | 60 |
Totals | 2076 | 278/2088 (13%) | 2882/8066 (36%) | Â |