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Table 1 Asymptomatic shedding of infectious HSV-1 detected by cell culture from mouth swabs of healthy subjects

From: HSV-1 latent rabbits shed viral DNA into their saliva

Author(s), Year

N

Individuals: total positive/total subjects

Shedding frequency: total positiveswabs/total swabs

Mouth swabs frequency: numberof swabs/subject

Buddingh et al., 1953 [56]

368*

30/368 (8.2%)

30/368 (8.2%)

one

Buddingh et al., 1953 [56]

185**

5/185 (2.4%)

5/185 (2.7%)

one

Kaufman et al., 1967 [57]

35

6/35 (17.1%)

6/700 (0.9%)

20

Lindgren et al., 1968 [58]

418

8/418 (1.9%)

8/2204 (0.4%)

5-6

Douglas & Couch, 1970 [59]

10

8/10 (80%)

11/494 (2.2%)

~49

Hatherley et al., 1980 [60]

384

37/384 (9.6%)

47/1536 (3.1%)

4

Spruance, 1984 [61]

8

8/8 (100%)

47/637 (7.4%)

105

Kameyama et al., 1988 [62]

110

5/110 (4.5%)

70/7805 (0.9%)

71

Tateishi et al., 1994 [63]

1000

27/1000 (2.7%)

27/1000 (2.7%)

one

Okinaga, 2000 [64]

10

4/10 (40%)

4/870 (0.5%)

87

Total

2528

138/2528 (5.5%)

255/15799 (1.6%)

 
  1. *adults.
  2. **children.