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Table 1 Asymptomatic shedding of infectious HSV-1 detected by cell culture from mouth swabs of healthy subjects

From: HSV-1 latent rabbits shed viral DNA into their saliva

Author(s), Year N Individuals: total positive/total subjects Shedding frequency: total positiveswabs/total swabs Mouth swabs frequency: numberof swabs/subject
Buddingh et al., 1953 [56] 368* 30/368 (8.2%) 30/368 (8.2%) one
Buddingh et al., 1953 [56] 185** 5/185 (2.4%) 5/185 (2.7%) one
Kaufman et al., 1967 [57] 35 6/35 (17.1%) 6/700 (0.9%) 20
Lindgren et al., 1968 [58] 418 8/418 (1.9%) 8/2204 (0.4%) 5-6
Douglas & Couch, 1970 [59] 10 8/10 (80%) 11/494 (2.2%) ~49
Hatherley et al., 1980 [60] 384 37/384 (9.6%) 47/1536 (3.1%) 4
Spruance, 1984 [61] 8 8/8 (100%) 47/637 (7.4%) 105
Kameyama et al., 1988 [62] 110 5/110 (4.5%) 70/7805 (0.9%) 71
Tateishi et al., 1994 [63] 1000 27/1000 (2.7%) 27/1000 (2.7%) one
Okinaga, 2000 [64] 10 4/10 (40%) 4/870 (0.5%) 87
Total 2528 138/2528 (5.5%) 255/15799 (1.6%)  
  1. *adults.
  2. **children.