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Figure 3 | Virology Journal

Figure 3

From: Sublingual immunization with recombinant adenovirus encoding SARS-CoV spike protein induces systemic and mucosal immunity without redirection of the virus to the brain

Figure 3

SARS-CoV neutralizing activity of Sera. Mice were immunized three times with rADV-S 2 × 107 PFU by s.l., i.n., or i.m. route. Sera were tested to measure the Abs that would neutralize the infectivity of 100 TCID50 of SARS-CoV in Vero cell monolayers. Neutralization titers were determined by the CPE of SARS-CoV on Vero cell. The dotted line indicates the limitation of detection. The results are expressed as the means + SD.

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