Activity of human IVIGs against HCV entry into Huh7.5, tested through direct interaction between viral particles and proteins. All panels contain DNA ladder (lane 1), negative control (lane 2) and amplified 174 bp of HCV in positive control (lane 3). (A) Lanes 4–9 show the direct interaction between HCV and IVIG-1, IVIG-2, and IVIG-3 at concentrations 0.5 and 1.0 mg/ml, respectively. (B). Lanes 4–9 represent cLf, IgGs, lactalbumin, human IVIG-1, IVIG-2 IVIG-3 at concentrations of 1.0 mg/ml, respectively. (C) Activity of camel casein against HCV entry into PBMCs and Huh7.5 cells. Infected PBMCs incubated with casein at concentrations of 0.5 and 1.0 mg/ml (lanes 4 and 5) and Huh7.5 cells incubated with casein at concentrations of 0.5 and 1.0 mg/ml (lanes 6 and 7).