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Table 2 Immunogenetic analysis of human anti-V3 monoclonal antibodies

From: Production and characterization of human anti-V3 monoclonal antibodies from the cells of HIV-1 infected Indian donors

#

1mAb

Specificity

Isotype

2IGHV

3CDRH3

1

277

V3 (gp120)

IgG1 κ

3-30*03

ATLPVVTPATEPFDF

2

903

V3 (gp120)

IgG1 κ

3-30*03

AKHYAEGGLDV

3

904

V3 (gp120)

IgG1 λ

1-8*01

ARFALQSYIVSTDSYDIDY

  1. 1Three anti-V3 monoclonal Abs listed were derived from HIV-1 infected Indian donors.
  2. 2Immunoglobulin gene usage for heavy (IGHV) and amino acid sequences of 3CDRH3 domains was determined using IMGT system; an asterisk indicates allele.