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Figure 2 | Virology Journal

Figure 2

From: NDV-induced apoptosis in absence of Bax; evidence of involvement of apoptotic proteins upstream of mitochondria

Figure 2

NDV infection leads to translocation of Bax and release of cytochrome c into cytosol in colon cancer cells. Infected wt HCT116, HCT116 Bax −/− and HT29 cells (18 h, 36 h and 48 h post-infection) were subjected to subcellular fractionation. The cytosolic samples were analyzed by Western blotting with anti-Bax clone 2D2 and anti-cytochrome c clone 7H8 antibodies. Absence of Bax in HCT116 Bax−/− cells was also checked.

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