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Table 2 Summary Chart of patients

From: Treatment and follow up of children with chronic hepatitis C in Albania

Patients

Age

Sex

Diagnosis

HCV-RNA

Liver Biopsy

Treatment

Side effects

HCV-RNA

Genotype

1

11 y

M

Non-Hodgking lymphoma

1.5 × 106 copies /ml

Metavir**A1F1

INFα2b***Ribavirin

Leucopenia

Not detected

 

2

5 y

M

Non-Hodgking lymphoma

1.8 × 106 copies /ml

Metavir A2F2

INFα2b***Ribavirin

None

Detected

1B

3

5 y

M

Testicular teratocarcinoma

761,000 copies/ml

Metavir A2F0

INFα2b***Ribavirin

None

Not detected

 

4

6 y

F

Meduloblastoma

6.3 × 104 copies/ml

Metavir A1F2

INFα2b***Ribavirin

Leucopenia headache

Not detected

 

5

12 y

M

Testicular seminoma

9.2 × 104 copies/ml

Metavir A2F1

INFα2b***Ribavirin

Fever

Not detected

 

6

11 Y

M

Leukemia

3,600 copies/ml

Metavir A1F1

INFα2b***Ribavirin

None

Not detected

 

7

10 y

F

Non-Hodgkin lymphoma

1.1 × 106 copies /ml

Metavir A3F2

INFα2b***Ribavirin

None

Not detected

1B

8

6 y

F

Leukemia

1.8 × 106 copies /ml

Metavir A2F1

INFα2b***Ribavirin

None

Not detected

 

9

3 y

M

Hemolytic anemia

1.5 x106 copies /ml

Metavir A1F2

INFα2b***Ribavirin

None

Not detected

 

10

8 y

M

Gaucher

6.8 × 105 copies/ml

Metavir A2F1

INFα2b***Ribavirin

None

Not detected

 

11

8 y

M

Leukemia

1.6 × 106 copies /ml

Metavir A2F1

INFα2b***Ribavirin

Myalgia

Not detected

1B

12

11 y

M

Unknown

1.8 × 106 copies /ml

Metavir A1F2

INFα2b***Ribavirin

Headache

Not detected

 

13

10 y

M

Leukemia

56,700 copies /ml

Metavir A2F2

INFα2b***Ribavirin

Fever

Not detected

 

14

15 y

F

Faringeal Ewing -sarcoma

9.3 × 105copie/ ml

Metavir A1F0

PEGINFα2b *** Ribavirin

None

Not detected

 

15

10 y

M

Leukemia

1.8 × 106 copies /ml

Metavir A2F1

INFα2b***Ribavirin

None

Not detected

 

16

10 y

M

Unknown

1.5 x106 copies /ml

Metavir A2F1

INFα2b***Ribavirin

None

Not detected

 

17

8 Y

M

Infantile fibrosis

2.5 x106 copies /ml

Metavir A2F2

PEGINFα2b *** Ribavirin

Fever, Cramps, Vomiting

Not detected

 
  1. *HCV-RNA are shown at the beginning and at the end of treatment. At the end we had only one patient with positive HCV RNA. ETVR = 94%. To each patient is performed an other HCV RNA of control (6 months after treatment to determine SVR) which has resulted positive for three patients. SVR was approximately 83%
  2. ** METAVIR is a histopathological score which expresses the rank of inflammation (A) and hepatic fibrosis (F) in cases of hepatitis C, etc.. Missing -A0, A1-minimum, A2-moderate; A3-severe; F0-no fibrosis; F1-portal fibrosis non-septal l; F2-portal fibrosis with few septal fibrosis; F3- septal fibrosis without cirrhosis, F4-cirrhosis
  3. ***Multi-transfusion patient (patient who has received more than 3 units of blood products
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Virology Journal

ISSN: 1743-422X