Identification of swine influenza A virus and Stenotrophomonas maltophilia co-infection in Chinese pigs

Table 2 Virus, clinical signs, virus replication, transmission and seroconversion of guinea pigs

Inoculum	Inoculated guinea pigs			Contact guinea pigs		Transmission
Inoculum	Clinical signs	Peak mean nasal wash titer ± SD (day)^**	Seroconversion (HI titer range)^***	Virus detected in nasal wash^****	Seroconversion (HI titer range)	Transmission
Swine influenza virus (SIV)	None	5.50 ± 0.6 (2)	3/3^*(40)	0/3	0/3	None
SIV + S. maltophilia	Depression	6.25 ± 0.4 (2)	3/3 (40–80)	0/3	0/3	None

^*Number of positive guinea pigs/total number; ^**Peak nasal wash titers are expressed as the mean log₁₀EID₅₀/mL ± SD; ^***Serum was collected on day 14 p.i. for the virus inoculated group and on day 21 p.i. for the contact group, and homologous strains were used to detect SIV seroconversion with chicken red blood cells in hemagglutination inhibition assays. ^****The lower limit of detection was 10^1.5 EID₅₀/mL.

ISSN: 1743-422X