Table 1 Comparison of the genome segments and encoded proteins of BTV, YUOV, TRBV, KEMV and GIV
BTV (insect-transmitted) | YUOV (insect-transmitted) | TRBV (tick-transmitted) | KEMV (tick-transmitted) | GIV (tick-transmitted) | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Segment 1 | VP1 (Pol) | 150 kDa | RNA-dep.-RNA- Polymerase | Segment 1 | VP1 (Pol) | 151 kDa | RNA-dep.-RNA- Polymerase | Segment 1 | VP1 (Pol) | 146 kDa | RNA-dep.-RNA- Polymerase | Segment 1 | VP1 (Pol) | 146 kDa | RNA-dep.-RNA- Polymerase | Segment 1 | VP1 (Pol) | 147 kDa | RNA-dep.-RNA- Polymerase |
3944 bp | ACR58458 | 1302 AA | 3393 bp | YP_443925 | 1315 AA | 3892 bp | HQ266581 | 1284 AA | 3896 bp | HQ266591 | 1285 AA | 3897 bp | ADM88592 | 1285 AA | |||||
Segment 2 | VP2 | 111 kDa | Outer shell | Segment 2 | VP2 (T2) | 107 kDa | Inner shell | Segment 2 | VP3 (T2) | 102 kDa | Inner shell | Segment 2 | VP3 (T2) | 103 kDa | Inner shell | Segment 2 | VP2 (T2) | 103 kDa | Inner shell |
2953 bp | ACR58459 | 956 AA | 2900 bp | YP_443926 | 940 AA | 2793 bp | HQ266582 | 908 AA | 2792 bp | HQ266592 | 908 AA | 2794 bp | ADM88593 | 908 AA | |||||
Segment 3 | VP3 (T2) | 103 kDa | Inner shell | Segment 3 | VP3 | 100 kDa | Outer shell | Segment 3 | VP4 (CaP) | 72 kDa | Capping Enzyme | Segment 3 | VP4 (CaP) | 72 kDa | Capping Enzyme | Segment 3 | VP3 (CaP) | 73 kDa | Capping Enzyme |
2772 bp | ACR58460 | 901 AA | 2688 bp | YP_443927 | 873 AA | 1935 bp | HQ266583 | 628 AA | 1934 bp | HQ266593 | 632 AA | 1936 bp | ADM88594 | 635 AA | |||||
Segment 4 | VP4 (CaP) | 75 kDa | Capping Enzyme | Segment 4 | VP4 (CaP) | 74 kDa | Capping Enzyme | Segment 4 | NS1 (TuP) | 62 kDa | Formes Tubules | Segment 4 | VP2 | 63 kDa | Outer shell | Segment 4 | NS1 (TuP) | 60 kDa | Formes Tubules |
1980 bp | ACR58461 | 644 AA | 1993 bp | YP_443928 | 645 AA | 1734 bp | HQ266584 | 529 AA | 1730 bp | HQ266594 | 554 AA | 1731 bp | ADM88595 | 531 AA | |||||
Segment 5 | NS1 (TuP) | 64 kDa | Forms Tubules | Segment 5 | NS1 (TuP) | 67 kDa | Forms Tubules | Segment 5 | VP2 | 62 kDa | Outer shell | Segment 5 | NS1 (TuP) | 60 kDa | Formes Tubules | Segment 5 | VP4 | 62 kDa | Outer shell |
1769 bp | ACR58463 | 552 AA | 1957 bp | YP_443929 | 574 AA | 1730 bp | HQ266585 | 554 AA | 1719 bp | HQ266595 | 529 AA | 1722 bp | ADM88596 | 551 AA | |||||
Segment 6 | VP5 | 59 kDa | Outer shell | Segment 6 | VP5 | 59 kDa | Outer shell | Segment 6 | VP5 | 59 kDa | Outer shell | Segment 6 | VP5 | 59 kDa | Outer shell | Segment 6 | VP5 | 60 kDa | Outer shell |
1638 bp | ACR58462 | 526 AA | 1683 bp | YP_443930 | 535 AA | 1668 bp | HQ266586 | 537 AA | 1668 bp | HQ266596 | 537 AA | 1666 bp | ADM88597 | 537 AA | |||||
Segment 7 | VP7 (T13) | 39 kDa | Inner shell | Segment 7 | NS2 (ViP) | 48 kDa | Viral inclusion body matrix protein | Segment 7 | NS2 (ViP) | 41 kDa | Viral inclusion body matrix protein | Segment 7 | NS2 (ViP) | 41 kDa | Viral inclusion body matrix protein | Segment 7 | VP7 (T13) | 40 kDa | Inner shell |
1156 bp | ACR58464 | 349 AA | 1504 bp | YP_443931 | 435 AA | 1196 bp | HQ266587 | 368 AA | 1197 bp | HQ266597 | 368 AA | 1181 bp | ADM88598 | 357 AA | |||||
Segment 8 | NS2 (ViP) | 41 kDa | Viral inclusion body matrix protein | Segment 8 | VP7 (T13) | 40 kDa | Inner shell | Segment 8 | VP7 (T13) | 40 kDa | Inner shell | Segment 8 | VP7 (T13) | 40 kDa | Inner shell | Segment 8 | NS2 (ViP) | 39 kDa | Viral inclusion body matrix protein |
1125 bp | ACR58465 | 354 AA | 1191 bp | YP_443932 | 355 AA | 1184 bp | HQ266588 | 357 AA | 1183 bp | HQ266598 | 357 AA | 1172 bp | ADM88599 | 359 AA | |||||
Segment 9 | VP6 (Hel) | 36 kDa | ssRNA and dsRNA binding helicase | Segment 9 | VP6 (Hel) | 37 kDa | ssRNA and dsRNA binding helicase | Segment 9 | VP6 (Hel) | 33 kDa | ssRNA and dsRNA binding helicase | Segment 9 | VP6 (Hel) | 34 kDa | ssRNA and dsRNA binding helicase | Segment 9 | VP6 (Hel) | 34 kDa | ssRNA and dsRNA binding helicase |
1049 bp | ACR58466 | 329 AA | 1082 bp | YP_443933 | 338 AA | 1034 bp | HQ266589 | 312 AA | 1049 bp | HQ266599 | 317 AA | 1056 bp | AMD88600 | 321 AA | |||||
Segment 10 | NS3 | 26 kDa | Glycoprotein | Segment 10 | NS3 | 28 kDa | Glycoprotein | Segment 10 | NS3 | 23 kDa | Glycoprotein | Segment 10 | NS3 | 23 kDA | Glycoprotein | Segment 10 | NS3 | 19 kDa | Glycoprotein |
822 bp | ACR58467 | 229 AA | 825 bp | YP_443934 | 253 AA | 705 bp | HQ266590 | 214 AA | 707 bp | HQ266600 | 214AA | 703 bp | ADM88602 | 171 AA | |||||