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Table 1 Frequency of SIV antigen-specific cytokine producing cells in vaccinated animals ^

From: Increased cellular immune responses and CD4+ T-cell proliferation correlate with reduced plasma viral load in SIV challenged recombinant simian varicella virus - simian immunodeficiency virus (rSVV-SIV) vaccinated rhesus macaques

Animal group SIV Antigen Mono* d14pi doc d231pc Bi ** d14pi doc d231pc
Experimental (EG) Env CD4 0.50% 0.66% 0.12% CD4 0.10% 0.01% 0.03%
  Env CD8 0.08% 0.18% 0.02% CD8 0.01% 0.03% 0.00%
  Gag CD4 0.86% ND ND CD4 0.79% ND ND
  Gag CD8 0.43% ND ND CD8 0.18% ND ND
Control (CG) Env CD4 0.00% 0.00% 0.19% CD4 0.00% 0.00% 0.00%
  Env CD8 0.00% 0.00% 0.05% CD8 0.00% 0.00% 0.00%
  Gag CD4 0.06% 0.00% 0.00% CD4 0.05% 0.00% 0.00%
  Gag CD8 0.05% 0.00% 0.00% CD8 0.01% 0.00% 0.00%
  1. (^) - Percentages are calculated means for each animal group.
  2. Mono* - Monofunctional cytokine producing cells.
  3. Bi** - Bifunctional cytokine producing cells.
  4. ND – Not determined.
  5. d14pi – d14 post-inoculation.
  6. doc – day of challenge.
  7. d231pc – d231 post-challenge.