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Table 1 Frequency of SIV antigen-specific cytokine producing cells in vaccinated animals ^

From: Increased cellular immune responses and CD4+ T-cell proliferation correlate with reduced plasma viral load in SIV challenged recombinant simian varicella virus - simian immunodeficiency virus (rSVV-SIV) vaccinated rhesus macaques

Animal group

SIV Antigen

Mono*

d14pi

doc

d231pc

Bi **

d14pi

doc

d231pc

Experimental (EG)

Env

CD4

0.50%

0.66%

0.12%

CD4

0.10%

0.01%

0.03%

 

Env

CD8

0.08%

0.18%

0.02%

CD8

0.01%

0.03%

0.00%

 

Gag

CD4

0.86%

ND

ND

CD4

0.79%

ND

ND

 

Gag

CD8

0.43%

ND

ND

CD8

0.18%

ND

ND

Control (CG)

Env

CD4

0.00%

0.00%

0.19%

CD4

0.00%

0.00%

0.00%

 

Env

CD8

0.00%

0.00%

0.05%

CD8

0.00%

0.00%

0.00%

 

Gag

CD4

0.06%

0.00%

0.00%

CD4

0.05%

0.00%

0.00%

 

Gag

CD8

0.05%

0.00%

0.00%

CD8

0.01%

0.00%

0.00%

  1. (^) - Percentages are calculated means for each animal group.
  2. Mono* - Monofunctional cytokine producing cells.
  3. Bi** - Bifunctional cytokine producing cells.
  4. ND – Not determined.
  5. d14pi – d14 post-inoculation.
  6. doc – day of challenge.
  7. d231pc – d231 post-challenge.