Figure 1
From: Disassociation of the SV40 Genome from Capsid Proteins Prior to Nuclear Entry
A representative infected cell at 12 hours post-infection. Perinuclear BrdU-labeled SV40 genomes are associated with VP2/3. BrdU-labeled SV40 genomes are seen in nuclei. However, parental VP2/3 is not seen in nuclei that contain viral genomes. The outline of the nucleus is delineated in the phase contrast image by the nuclear envelope and underlying nuclear lamina. It is further highlighted by the hashed white line drawn on the merge image. Samples stained for BrdU (Cy3) and VP2/3 (FITC). The size bar corresponds to 10 microns.