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Figure 3 | Virology Journal

Figure 3

From: The soluble amino-terminal region of HVEM mediates efficient herpes simplex virus type 1 infection of gD receptor-negative cells

Figure 3

Specificity of sHA 102 -mediated entry. (A) Comparison of sHA102-mediated CHO-K1 infection by KOS/tk12 and a mutant-gD derivative impaired for HVEM binding, KOS-Rid1/tk12, at MOIs of 3. (B) Inhibition of sHA102-mediated infection by soluble gD. sHA102 and sgD287 at the indicated concentrations were incubated with KOS/tk12 virus at 4°C prior to the addition of CHO-K1 cells (MOI = 3) and incubation at 37°C. Infection was determined by ONPG assay. Values are averages of triplicate determinations.

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