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Figure 2 | Virology Journal

Figure 2

From: Non structural protein of avian influenza A (H11N1) virus is a weaker suppressor of immune responses but capable of inducing apoptosis in host cells

Figure 2

A Venn-diagram representation of the number of host genes and the major pathways affected by NS1 protein of the two Influenza A viruses (H5N1 and H11N1) compared to mock. The number of genes exclusively affected by vector (mock) are shown in light green (5) were found to be mainly involved in stress response. Genes exclusively affected by the transfection of NS1 protein are represented in light red (16) for H5N1-NS1 and light blue (10) for H11N1-NS1; Gene ontology analysis showed that these were mainly involved in apoptosis, immune response and signal transduction processes. The differentially expressed genes common between vector and H11N1-NS1 are shown in dark blue (1) whereas, genes common between vector and H5N1-NS1 are shown in dark green (8). Three genes were common in transfections with all the different plasmid constructs. All analyses are in comparison with control untransfected cells.

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Virology Journal

ISSN: 1743-422X