Table 2 Conservation of patterns/motifs predicted on NS5A, described in percentage of sequences
From: New insights regarding HCV-NS5A structure/function and indication of genotypic differences
Motif/pattern name | Presence | Conserved Positions | No. of sites in same sequence |
|---|---|---|---|
N-glycosylation | 95,65% | 69, 268 (90%) | Two up to six |
cAMP/cGMP-dependent phosphorylation | 95,65% | 357 (90, 14%) | One up to two |
PKC phosphorylation | 100% | 71, 238 (98, 84%) | Five up to eight |
CKII phosphorylation | 100% | - | Four up to eight |
Tyrosine kinase phosphorylation | 99,99% | 122 or 123(99, 99%) | Four up to eight |
N-myristoylation | 100% | - | Four up to eight |
Cell attachment sequence | 100% | 48 (100%) | 1 |