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Table 1 Neutralizing antibody titers in mice immunized with recombinant baculoviruses (mean values of groups of 4 mice)

From: Induction of antigen-specific immune responses in mice by recombinant baculovirus expressing premembrane and envelope proteins of West Nile virus

Vaccine

Anti-WNVb

Anti-JEVc

3 weeks

6 weeks

3 weeks

6 weeks

Bac-G-prM/E 109

16

44

4

10

Bac-G-prM/E 108

8

22

< 2

6

Bac-prM/E 109

11

30

< 2

7

Bac-prM/E 108

5

12

< 2

4

E-DIII pro.

4

8

< 2

< 2

Bac-G-EGFP 109

< 2

< 2

< 2

< 2

  1. Samples were taken three weeks and six weeks after the primary immunization.a
  2. a plaque-reduction neutralization tests (PRNTs);
  3. b WNV (NY99 strain)-specific neutralizing antibodies; c JEV(P3 strain)-specific neutralizing antibodies; < 2, not detected.
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Virology Journal

ISSN: 1743-422X