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Table 2 Nucleotide and aminoacid divergences

From: Molecular characterization of hepatitis B virus X gene in chronic hepatitis B patients

n

Group

X gene(Non-overlapped region)

X gene(Over-lapped region with pol gene)

CompleteX protein

% nucleotide divergence

% nucleotide divergence

% aminoacid divergence

Mean ± SD

Mean ± SD

Mean ± SD

3

F4 HBeAg(+)

1.9 ± 0.9

0.6 ± 0.4

2.28 ± 1.01

5

F4 HBeAg(−)

5.7 ± 1.7 (*)

3.2 ± 0.9 (*)

7.00 ± 1.54 (*)

5

F1b HBeAg(+)

1.4 ± 0.6

0.7 ± 0.3

1.89 ± 0.70

4

D HBeAg(+)

1.9 ± 0.7

2.5 ± 0.7

3.54 ± 0.96

7

D HBeAg(−)

4.4 ± 1.2 (*)

2.1 ± 0.6

5.66 ± 1.35 (*)

5

A HBeAg(+)

1.3 ± 0.6

0.8 ± 0.4

2.04 ± 0.77

3

A HBeAg(−)

1.9 ± 0.9

2.1 ± 0.8 (*)

3.43 ± 1.32 (*)

  1. Genetic distances within genotypes (HBeAg status + or -) in overlapped and non-overlapped regions (analyzing nucleotides), and in the whole X protein (aminoacids). (*) denotes statistically significant differences between HBeAg +/− groups within each genotype.