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Table 1 The positive detection rate of HEV71- and CVA16-IgM antibodies by the IgM-capture ELISA.

From: Evaluation of human enterovirus 71 and coxsackievirus A16 specific immunoglobulin M antibodies for diagnosis of hand-foot-and-mouth disease

 

No. of positive/No. of sera

Positive predictive value (95% confidence interval)

Negative predictive value (95% confidence interval)

IgM-capture ELISAs

HEV71 infected sera

CVA16 infected sera

Other enterovirus infected sera

Respiratory virus infectious sera

  

HEV71-IgM

233/249

38/122

14/49

2/105

81.3% (76.9-85.1%)

91.0% (87.5-93.8%)

CVA16 -IgM

58/211

91/125

16/48

3/105

54.4% (48.3-60.9%)

88.6% (85.1-91.4%)

  1. Note: The data were collected during the first 90 days of disease.