Figure 1
Cross-reactivity reduced vaccines elicit DENV specific neutralizing IgG. (A) DENV-2 16681 neutralizing-antibody (Nt-Ab) titers elicited by WT and cross-reactivity reduced vaccines as determined by 50% FRμNT. (B) DENV-1 56BC94/95 Nt-Ab titers. (C) DENV-3 116RC1396 Nt-Ab titers. (D) DENV-4 H241 Nt-Ab titers. Data are expressed as GMT +/− 95%CI. for n = 10. Kruskal-Wallis test and Dunn’s post test was used to analyze data. p < 0.05 were considered significant; single asterisk, p < 0.05.