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Figure 2 | Virology Journal

Figure 2

From: MicroRNAs and hepatitis C virus: Toward the end of miR-122 supremacy

Figure 2

miR-196b and hepatitis C virus infection. After activation by hepatitis C virus (HCV) infection, interferon (IFN) pathway stimulates the expression of miR-196b. This miRNA inhibits HCV replication either directly via a target site on the HCV RNA or indirectly via Bach1 down-regulation and heme oxygenase-1 (HMOX1) up-regulation. The indirect pathway seems to be predominant. How HCV responds to miR-196b targeting remains to be fully investigated

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