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Figure 1 | Virology Journal

Figure 1

From: The HIV-1 Nef Protein Interacts with two components of the 40S small ribosomal subunit, the RPS10 protein and the 18S rRNA

Figure 1

HIV-1 Nef inhibits translation in vitro .

The level of translation of the luciferase mRNA has been measured in the presence of increasing concentrations of rNef, rVpr or recombinant ovalbumin in RRL. Recombinant HIV-1 Vpr and ovalbumin were used to test the specificity of Nef action on translation. In addition an inactive form of Nef was obtained by heating at 100°C for 5 min (HI).

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