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Table 2 Antiviral effect of prestimulation with Toll-like receptor specific ligands against influenza A/Puerto Rico/8/34.

From: Toll-like receptor pre-stimulation protects mice against lethal infection with highly pathogenic influenza viruses

TLR ligand

Receptor

Ratio of MLD50(log10EID50) between LPS-pretreated and mock-treated mice

Synthetic mycoplasmal lipoprotein (FSL-1)

TLR2

1.0

Synthetic analog of dsRNA (Poly(I:C))

TLR3

0.66

LPS from E. coli K12 msbB

TLR4

1.0

LPS from E. coli serotype O111:B4

 

0.66

Guanosine analog (loxoribine)

TLR7

0.66

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Virology Journal

ISSN: 1743-422X