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Table 2 Efficacy of antiviral drugs against Korean echovirus 5

From: Genetic diversity of a Korean echovirus 5 isolate and response of the strain to five antiviral drugs

Compounds

IC50a

CC50b

TIc

Azidothymidine

NDd

>100

-

Acyclovir

NDd

>100

-

Amantadine

1 ± 0.42

>100

100

Lamivudine

NDd

>100

-

Ribavirin

22 ± 1.36

>100

4.55

  1. These results are the mean ± S.D. (n = 3)
  2. a Concentration of compound in μg/mL producing 50% inhibition of virus-induced cytopathic effects.
  3. b The 50% cytotoxic concentration for target cells in μg/mL.
  4. C Therapeutic index (TI) = CC50/IC50
  5. d Not Determined
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Virology Journal

ISSN: 1743-422X