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Table 2 Efficacy of antiviral drugs against Korean echovirus 5

From: Genetic diversity of a Korean echovirus 5 isolate and response of the strain to five antiviral drugs

Compounds IC50a CC50b TIc
Azidothymidine NDd >100 -
Acyclovir NDd >100 -
Amantadine 1 ± 0.42 >100 100
Lamivudine NDd >100 -
Ribavirin 22 ± 1.36 >100 4.55
  1. These results are the mean ± S.D. (n = 3)
  2. a Concentration of compound in μg/mL producing 50% inhibition of virus-induced cytopathic effects.
  3. b The 50% cytotoxic concentration for target cells in μg/mL.
  4. C Therapeutic index (TI) = CC50/IC50
  5. d Not Determined