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Figure 1 | Virology Journal

Figure 1

From: Cellular immune responses in patients with hepatitis B surface antigen seroclearance induced by antiviral therapy

Figure 1

Ex vivo IFN-γ ELISPOT responses to HBV S and C open reading frame peptide pools and recombinant HBV proteins. (A) Comparison of subjects with HBsAg seroclearance, immunotolerant HBV carriers and inactive HBsAg carriers. Each line represents the mean number of spot-forming cells induced by each stimulus. Each dotted line represents the cut-off value for a positive test in the ELISPOT assay. (B) Comparison of the frequency of positive responses obtained in HBsAg seroclearance and control populations. (C) Comparison of the mean number of spots/well from the subjects with positive tests in each group. Each bar represents the mean ± SD.

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