Inoculated viruses | No. of chickens | Days p.i. (Health status) | Virus recovery (log EID50/g) | ||||||
---|---|---|---|---|---|---|---|---|---|
Brain | Trachea | Lung | Liver | Kidney | Colon | Bloodc | |||
rgY55 (H9N2) | 3 | 3 (sacrificed) | -, -, -b | -, -, ≦ 1.7 | -, -, - | -, -, - | -, -, - | -, -, - | -, -, - |
rgY55sub (H9N2) | 3 | 3 (sacrificed) | -, -, - | 5.5, 5.7, 6.5 | -, 6.7, 2.7 | -, 2.7, - | -, -, 2.5 | -, -, - | -, -, - |
rgY55sub-P10 (H9N2) | 3 | 3 (sacrificed) | -, -, - | -, -, 3.3 | -, 3.7, 6.0 | -, -, 2.5 | -, 4.3, 4.5 | -, 3.3, 4.5 | -, -, - |
rgVac1 (H5N1) | 3 | 3 (sacrificed) | -, -, - | -, -, - | -, -, - | -, -, - | -, -, - | -, -, - | -, -, - |
rgVac1sub (H5N1) | 3 | 3 (sacrificed) | -, -, 2.7 | -, -, - | -, -, 2.5 | -, -, - | -, -, - | -, -, ≦ 2.0 | -, -, - |
rgVac1sub-P2 (H5N1) | 2 | 3 (sacrificed) | -, - | -, - | -, - | -, - | -, - | -, - | -, - |
1a | 3 (sacrificed) | 5.0 | 3.8 | 5.0 | 5.2 | 7.5 | 5.2 | 4.3 | |
rgVac1sub-P3 (H5N1) | 2a | 3 (dead) | 5.7, 6.7 | 5.3, 6.5 | 4.7, 8.2 | 3.5, 6.0 | 7.3, 9.0 | 5.5, 6.5 | NAd |
1a | 3 (sacrificed) | 6.3 | 6.5 | 6.7 | 6.5 | 6.5 | 6.5 | 5.8 | |
rgVac1ins (H5N1) | 3 | 3 (sacrificed) | -, ≦ 2.6, - | -, 3.5, - | -,3.3, 3.7 | -, -, 3.5 | -, 2.7, 3.0 | -, 3.0, 2.5 | -, ≦ 1.6, 2.8 |
rgVac1ins-P2 (H5N1) | 1a | 2 (dead) | 3.5 | 3.4 | 4.7 | 3.7 | 4.8 | 4.7 | NA |
1a | 3 (sacrificed) | 3.8 | 3.7 | 3.0 | ≦ 2.0 | 4.7 | ≦ 2.0 | - | |
1 | 3 (sacrificed) | - | - | - | - | - | - | - | |
rgVac1ins-P3 (H5N1) | 3a | 3 (sacrificed) | 3.4, 4.7, 5.5 | 4.7, 3.5, 4.2 | 5.5, 5.2, 6.7 | 4.3, 4.5, 5.7 | 4.5, 4.7, 5.2 | 5.3, 4.5, 5.3 | 3.0, 2.5, 3.5 |