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Table 4 Pathogenicity of each virus for chicken via intranasal route

From: H9N2 influenza virus acquires intravenous pathogenicity on the introduction of a pair of di-basic amino acid residues at the cleavage site of the hemagglutinin and consecutive passages in chickens

Inoculated viruses

Seroconversion at 14 d.p.i.a

Clinical signs

Mortality (dead days)

rgY55 (H9N2)

3/3b

0/3

0/3

rgY55sub (H9N2)

3/3

0/3

0/3

rgY55sub-P10 (H9N2)

3/3

0/3

0/3

rgVac1 (H5N1)

0/3

0/3

0/3

rgVac1sub (H5N1)

1/3

0/3

0/3

rgVac1sub-P2 (H5N1)

0/1

2/3

2/3 (4, 11)

rgVac1sub-P3 (H5N1)

1/1

3/3

2/3 (7, 8)

rgVac1ins (H5N1)

1/3

0/3

0/3

rgVac1ins-P2 (H5N1)

1/1

2/3

2/3 (8, 11)

rgVac1ins-P3 (H5N1)

0/1

2/3

2/3 (4, 6)

  1. a Examined for the survived chickens by HI test and ELISA.
  2. b The number of positive animals/total
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Virology Journal

ISSN: 1743-422X