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Figure 8 | Virology Journal

Figure 8

From: Reduced inflammation and altered innate response in neonates during paramyxoviral infection

Figure 8

RLR protein expression was delayed in neonatal lungs, and type I interferon was reduced on day 3 post-infection. Adult (white bars) and neonatal mice (black bars) were infected as described in Figure 1. a) On the indicated days, lungs were homogenized and equivalent amounts of protein were analyzed by SDS-PAGE and western blot analysis. b) Whole lung RNA, from adults (white bars), neonates (black bars) and naïve age-matched neonatal controls (striped bars), was analyzed for IFN-β expression by qPCR. All values represent the mean ± SD; *, significant difference from corresponding adult sample.

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