Figure 7
From: Reduced inflammation and altered innate response in neonates during paramyxoviral infection
TLR mRNA expression was similar in adult and neonatal lungs, but RLR mRNA expression was delayed in neonatal lungs. Adult and neonatal C57BL/6 mice were infected as described in Figure 1. Whole lung RNA isolated from adults (white bars), neonates (black bars) and naïve age-matched neonatal controls (striped bars) was analyzed by real-time PCR for TLR expression a) TLR-3, TLR-7, and TLR-8, and RLR expression b) LGP2, MDA-5, and RIG-I. All values represent the mean ± SD; *, significant difference from corresponding adult sample.