The lung tissue pathological changes. A: the unimmunized infected group (×200). The lung tissue pathological changes from the unimmunized infected groups died on day 6. Necrotizing interstitial pneumonia was found in all cases of death. The pulmonary tissue exhibited hyperemia,hemorrhage,and inflammatory exudation. B: the 200 μg multi-mimotope immunized infected group (×200). The lung tissue pathological changes from the 200 μg multi-mimotopes immunized infected group on day 14. Showing the lung inflammation level were significantly decreased compared with those of their matched unimmunized infected group.