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Table 1 The infectivity and pathogenicity of O/CHN/2010/33-OP

From: The infectivity and pathogenicity of a foot-and-mouth disease virus persistent infection strain from oesophageal-pharyngeal fluid of a Chinese cattle in 2010

Group

Infected strain

Animals

dpi

Clinic symptom

Virus in OP fluid

Virus in lymph nodes

Virus in spinal cords

3ABC

NSP Ab

Type O

SP Ab

(LPB-ELISA)

Group 1

O/CHN/

2010/

33-OP

OP fluid

cattle

No.134

8

+

   

+

1:720

   

14

+

+

+

 

+

1:1024

  

cattle

No.184

8

-

-

  

+

1:360

   

14

-

-

+

 

+

1:1024

 

Direct contact

infection

pig

No.036

8

-

   

-

< 1:4

   

11

+

   

-

1:90

   

14

+

  

+

+

1:512

  

pig

No.039

8

-

   

-

< 1:4

   

11

-

   

-

1:45

   

14

-

  

+

-

1:180

  

pig

No.040

8

-

   

-

1:6

   

11

-

   

-

1:45

   

14

-

  

+

-

1:128

Group 2

O/CHN/2010/

33-OP cell strain

cattle

No.3

8

-

   

+

1:90

   

11

-

   

+

1: 90

   

14

-

+

+

 

+

1: 180

  

cattle

No.146

8

-

   

-

1:32

   

11

-

   

-

1:90

   

14

-

+

+

 

+

1:128

 

Direct contact

infection

pig

No.041

8

-

   

-

1:4

   

11

-

   

-

1:4

   

14

-

  

+

-

1:16

  

pig

No.046

8

-

   

-

1:12

   

11

-

   

-

1:6

   

14

-

  

+

-

1:6

  

pig

No.049

8

-

   

-

1:4

   

11

-

   

-

1:6

   

14

-

  

+

-

1:6

Group 3

O/CHN/2010/

33-OP cell strain

pig

No.029

4

+

   

/

/

   

5

+

   

/

/

   

14

+

  

+

+

1:180

  

pig

No.032

4

-

   

/

/

   

5

-

   

/

/

   

14

-

  

+

+

1:512

  

pig

No.033

4

-

   

/

/

   

5

-

   

/

/

   

14

-

  

+

+

1:128

Group 4

(control)

O/CHN/Mya98/

2010 cell strain

cattle

No.11

5

-

   

/

/

   

8

-

   

-

1:32

   

14

+

 

+

 

+

1:256

  

cattle

No.12

5

+

   

-

1:90

   

8

+

   

+

/

   

14

+

 

+

 

+

1:180

Group 5

(control)

O/CHN/Mya98/

2010 cell strain

pig

No.047

5

-

   

/

/

   

8

-

   

/

/

   

14

-

  

+

+

1:180

  

pig

No.048

5

-

   

/

/

   

8

+

   

-

1:45

   

14

+

  

+

+

1:360

  

pig

No.050

5

+

   

/

/

   

8

+

   

-

1:180

   

14

+

  

+

+

1:360

  1. Note: / undetected + positive - negative
  2. dpi : days post infection NSP: nonstructural protein SP: structural protein
  3. Ab: Antibody