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Table 1 The infectivity and pathogenicity of O/CHN/2010/33-OP

From: The infectivity and pathogenicity of a foot-and-mouth disease virus persistent infection strain from oesophageal-pharyngeal fluid of a Chinese cattle in 2010

Group Infected strain Animals dpi Clinic symptom Virus in OP fluid Virus in lymph nodes Virus in spinal cords 3ABC NSP Ab Type O SP Ab (LPB-ELISA)
Group 1 O/CHN/ 2010/ 33-OP OP fluid cattle No.134 8 +     + 1:720
    14 + + +   + 1:1024
   cattle No.184 8 - -    + 1:360
    14 - - +   + 1:1024
  Direct contact infection pig No.036 8 -     - < 1:4
    11 +     - 1:90
    14 +    + + 1:512
   pig No.039 8 -     - < 1:4
    11 -     - 1:45
    14 -    + - 1:180
   pig No.040 8 -     - 1:6
    11 -     - 1:45
    14 -    + - 1:128
Group 2 O/CHN/2010/ 33-OP cell strain cattle No.3 8 -     + 1:90
    11 -     + 1: 90
    14 - + +   + 1: 180
   cattle No.146 8 -     - 1:32
    11 -     - 1:90
    14 - + +   + 1:128
  Direct contact infection pig No.041 8 -     - 1:4
    11 -     - 1:4
    14 -    + - 1:16
   pig No.046 8 -     - 1:12
    11 -     - 1:6
    14 -    + - 1:6
   pig No.049 8 -     - 1:4
    11 -     - 1:6
    14 -    + - 1:6
Group 3 O/CHN/2010/ 33-OP cell strain pig No.029 4 +     / /
    5 +     / /
    14 +    + + 1:180
   pig No.032 4 -     / /
    5 -     / /
    14 -    + + 1:512
   pig No.033 4 -     / /
    5 -     / /
    14 -    + + 1:128
Group 4 (control) O/CHN/Mya98/ 2010 cell strain cattle No.11 5 -     / /
    8 -     - 1:32
    14 +   +   + 1:256
   cattle No.12 5 +     - 1:90
    8 +     + /
    14 +   +   + 1:180
Group 5 (control) O/CHN/Mya98/ 2010 cell strain pig No.047 5 -     / /
    8 -     / /
    14 -    + + 1:180
   pig No.048 5 -     / /
    8 +     - 1:45
    14 +    + + 1:360
   pig No.050 5 +     / /
    8 +     - 1:180
    14 +    + + 1:360
  1. Note: / undetected + positive - negative
  2. dpi : days post infection NSP: nonstructural protein SP: structural protein
  3. Ab: Antibody