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Table 1 The infectivity and pathogenicity of O/CHN/2010/33-OP

From: The infectivity and pathogenicity of a foot-and-mouth disease virus persistent infection strain from oesophageal-pharyngeal fluid of a Chinese cattle in 2010

Group Infected strain Animals dpi Clinic symptom Virus in OP fluid Virus in lymph nodes Virus in spinal cords 3ABC
NSP Ab
Type O
SP Ab
(LPB-ELISA)
Group 1 O/CHN/
2010/
33-OP
OP fluid
cattle
No.134
8 +     + 1:720
    14 + + +   + 1:1024
   cattle
No.184
8 - -    + 1:360
    14 - - +   + 1:1024
  Direct contact
infection
pig
No.036
8 -     - < 1:4
    11 +     - 1:90
    14 +    + + 1:512
   pig
No.039
8 -     - < 1:4
    11 -     - 1:45
    14 -    + - 1:180
   pig
No.040
8 -     - 1:6
    11 -     - 1:45
    14 -    + - 1:128
Group 2 O/CHN/2010/
33-OP cell strain
cattle
No.3
8 -     + 1:90
    11 -     + 1: 90
    14 - + +   + 1: 180
   cattle
No.146
8 -     - 1:32
    11 -     - 1:90
    14 - + +   + 1:128
  Direct contact
infection
pig
No.041
8 -     - 1:4
    11 -     - 1:4
    14 -    + - 1:16
   pig
No.046
8 -     - 1:12
    11 -     - 1:6
    14 -    + - 1:6
   pig
No.049
8 -     - 1:4
    11 -     - 1:6
    14 -    + - 1:6
Group 3 O/CHN/2010/
33-OP cell strain
pig
No.029
4 +     / /
    5 +     / /
    14 +    + + 1:180
   pig
No.032
4 -     / /
    5 -     / /
    14 -    + + 1:512
   pig
No.033
4 -     / /
    5 -     / /
    14 -    + + 1:128
Group 4
(control)
O/CHN/Mya98/
2010 cell strain
cattle
No.11
5 -     / /
    8 -     - 1:32
    14 +   +   + 1:256
   cattle
No.12
5 +     - 1:90
    8 +     + /
    14 +   +   + 1:180
Group 5
(control)
O/CHN/Mya98/
2010 cell strain
pig
No.047
5 -     / /
    8 -     / /
    14 -    + + 1:180
   pig
No.048
5 -     / /
    8 +     - 1:45
    14 +    + + 1:360
   pig
No.050
5 +     / /
    8 +     - 1:180
    14 +    + + 1:360
  1. Note: / undetected + positive - negative
  2. dpi : days post infection NSP: nonstructural protein SP: structural protein
  3. Ab: Antibody