Figure 5From: Rotavirus nonstructural protein 1 antagonizes innate immune response by interacting with retinoic acid inducible gene ISchematic diagram of the proposed mechanisms by which rotavirus NSP1 subverts host innate immunity. Shown are the targets of NSP1 involved in host innate immune signaling. NSP1, nonstructural protein 1 of rotavirus; RIG-I, retinoic acid inducible gene I;MDA5, melanoma differentiation-associated gene 5;MAVS, mitochondrial antiviral-signaling protein; IPS-1, IFNβ-promoter stimulator 1; IFN, interferon; IRF, interferon transcription factor; Ub, ubiquitin.Back to article page