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Figure 2 | Virology Journal

Figure 2

From: Rotavirus nonstructural protein 1 antagonizes innate immune response by interacting with retinoic acid inducible gene I

Figure 2

Rotavirus NSP1 inhibits RIG-I mediated IFN-β promoter activation. 293FT cells were transfected with pGL3-IFN-β-Luc along with plasmids encoding RIG-I (A and D), MDA5 (B and F), MAVS (C and E) and OSU NSP1 or SA11 NSP1ΔIRF3BD. pRL-SV40 was included as a control. At 36 h after transfection, the luciferase activities were measured as described in the Methods section. Results are expressed as folds of activation with standard deviations among triplicate samples.

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