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Table 1 Concise summary of the Immunization study of yeast derived HA protein in mice and rabbits

From: Yeast expressed recombinant Hemagglutinin protein of Novel H1N1 elicits neutralising antibodies in rabbits and mice

Animal group Sera sample Antibody titre HI titre# PRNT titre#
Mice group V1
(50μg/dose/animal)
Pre Immune <1:16 0 <16
  2 wks post Immunisation 1:512 32 NT*
  2 wks post booster 1:2048 32 256
Mice group V2
(10μg/dose/animal)
Pre Immune <1:16 0 <16
  2 wks post Immunisation 1:256 32 NT*
  2 wks post booster 1:1024 32 64
Mice control group Pre Immune <1:16 0 <16
  2 wks post Immunisation <1:16 0 NT*
  2 wks post booster <1:16 0 <16
Rabbit 1 (50μg/dose/animal) Pre Immune <1:16 0 <16
  2 wks post Immunisation 1:2048 32 NT*
  2 wks post booster 1:8192 64 256
Rabbit 2 (50μg/dose/animal) Pre Immune <1:16 0 <16
  2 wks post Immunisation 1:2048 32 NT*
  2 wks post booster 1:8192 64 256
Rabbit Control Pre Immune <1:16 0 <16
  2 wks post Immunisation <1:16 0 NT*
  2 wks post booster <1:16 0 <16
  1. NT* - Not tested; # HI and PRNT titres are the mean reciprocals obtained against the H1N1 virus isolated during the 2009 outbreak in India