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Figure 3 | Virology Journal

Figure 3

From: Sequence similarity between the erythrocyte binding domain of the Plasmodium vivax Duffy binding protein and the V3 loop of HIV-1 strain MN reveals a functional heparin binding motif involved in binding to the Duffy antigen receptor for chemokines

Figure 3

Polyanion inhibition of P. knowlesi invasion of DARC+ erythrocytes. The same polyanions used to inhibit the pvRII binding assay shown in Figure 2 were used in the P. knowlesi invasion assay. The inhibition of invasion was determined by subtracting the number of chemokine-treated DARC+ human erythrocytes invaded by P. knowlesi merozoites (per 2000 erythrocytes) from the number of untreated DARC+ human erythrocytes invaded by P. knowlesi merozoites, and dividing by the number of untreated, invaded erythrocytes.

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