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Table 1 IgG-secreting cells and total antigen secreting cells produced by immunization with pUCpGs10 and aluminium.

From: Enhancement of humoral immunity in mice by coupling pUCpGs10 and aluminium to the HCV recombinant immunogen

Group

ELISPOT assay(SFU/106)

FACS(%)

ELISA

 

Specific ASC

Total ASC

CD19+

CD27+

CD19+

CD38+

IL-6(pg/ml)

IL-10(pg/ml)

IgG titer

CpG+Alum

66.13 ± 26.66

111.25 ± 44.77

2.06 ± 0.34

46.42 ± 2.21

31.14 ± 34.57

249.75 ± 175.35

1:51200

CpG

40.25 ± 22.22

73 ± 50.58

1.15 ± 0.08

40.17 ± 6.40

15.74 ± 12.68

34.38 ± 2.29

1:9051

Alum

62.88 ± 17.06

125.75 ± 27.36

1.72 ± 0.49

38.91 ± 11.52

113.97 ± 101.98

241.50 ± 127.99

1:18102

PBS

24.13 ± 14.90

42.50 ± 38.54

1.29 ± 0.78

29.47 ± 8.49

5.88 ± .58

35.25 ± 9.36

1:6400