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Table 1 Humoral responses (anti-HCV IgG) in immunised groups detected by ELISA.

From: Effect of route of delivery on heterologous protection against HCV induced by an adenovirus vector carrying HCV structural genes

 

IgG Antibody titer

 

Ad (i.m.)

Ad (i.d.)

Ad (i.n.)

Ad (i.m.+i.m.)

Ad (i.m.+i.n.)

Ad (i.n.+i.m.)

Ad (id)/TTV(id)

Anti-core

50

50

50

50

50

3200

400

Anti-E1

100

100

25

200

200

100

1600

Anti-E2

100

100

25

800

400

100

1600

  1. Note: Antisera were collected 14 days post-immunization, and total IgG titres specific for the HCV antigen were determined by ELISA as described in the methods. Numbers represent titres of pooled sera from each group. Experiments were repeated at least three times and same results were obtained. The antibody titre was defined as the reciprocal of the serum dilution at which the absorbance (OD value) was twice that of sera in the non-immunized group.