| IgG Antibody titer |
---|
| Ad (i.m.) | Ad (i.d.) | Ad (i.n.) | Ad (i.m.+i.m.) | Ad (i.m.+i.n.) | Ad (i.n.+i.m.) | Ad (id)/TTV(id) |
---|
Anti-core | 50 | 50 | 50 | 50 | 50 | 3200 | 400 |
Anti-E1
| 100 | 100 | 25 | 200 | 200 | 100 | 1600 |
Anti-E2
| 100 | 100 | 25 | 800 | 400 | 100 | 1600 |
- Note: Antisera were collected 14 days post-immunization, and total IgG titres specific for the HCV antigen were determined by ELISA as described in the methods. Numbers represent titres of pooled sera from each group. Experiments were repeated at least three times and same results were obtained. The antibody titre was defined as the reciprocal of the serum dilution at which the absorbance (OD value) was twice that of sera in the non-immunized group.