Table 6 Comparison between CHC and HCC regarding HOMA-IR index >4 and high risk variables
From: Chronic hepatitis c genotype-4 infection: role of insulin resistance in hepatocellular carcinoma
Variables | CHC HOMA-IR >4 20(40%) | HCC HOMA-IR >4 26(52%) |
|---|---|---|
Age | Â | Â |
> 57 years | 13(65) | 17(65) |
Male gender: | 14(70) | 17 (65) |
Obese(>25 kg/m 2 ) | 16 (80) | 17(65) |
LFT (Mean ± SD) |  |  |
ALT (>37 IU/L) | 18(90) | 24(92) |
AST (>40 IU/L) | 18(90) | 26(100) |
T. Bil (> 1 mg/dL) | 13(65) | 26(100) |
INR (> 1-) | 18(90) | 26(100) |
GGT (>50 IU/L) | 17(85) | 26(100) |
Biochemical tests | Â | Â |
Fasting glucose (>110 mg/dL) | 20(100) | 26(100) |
Fasting insulin (>6IU/L) | 20(100) | 26(100) |
HbA1c (>7%) | 19(95) | 25(96) |
Cholesterol (> 200 mg/dL) | 14(70) | 15(58) |
TG(> 150 mg/dL) | 20(100) | 25(96) |
Tumor marker | Â | Â |
Serum AFP (>10 ng/mL) | 20(100) | 26(100) |
HCV RNA (viral load) N(%) | Â | Â |
Moderate | 12(60) | 19(73) |
High | 7(35) | 7(27) |
Stage of Fibrosis | Â | Â |
III+IV | 19(95) | 26(100) |