Figure 3

Regression analysis for IgM and IgG responses against number of days post-discharge for convalescent LF patients. Corrected mean OD₄₅₀ values for LASV-specific IgM (A.) and IgG (B.) levels in LF convalescent patients did not reveal any dependence with time post-discharge for immunoglobulins responses. Hypothesis tests for the slope of each regression line revealed zero slopes for both profiles, suggesting that IgM and IgG responses for convalescent patients remained relatively constant after discharge. The fitted intercept for the regression line shown in (A.) was 0.46 (SE = 0.09), which showed prolonged elevation in IgM responses for convalescent LF patients. The fitted intercept of 1.14 (SE = 0.06) for (B.) was indicative of a prolonged mature humoral response (IgG) in convalescent LF patients.