Table 2 Comparison of eight critical amino acids closely related to the neurovirulence of JEV in E protein between the virulent strains and the attenuated vaccine strain (SA14-14-2).
Strain | E107 | E138 | E176 | E177 | E264 | E279 | E315 | E439 |
|---|---|---|---|---|---|---|---|---|
SX09S-01 | Leu (L) | Glu (E) | Ile (I) | Thr (T) | Gln (Q) | Lys (K) | Ala (A) | Lys (K) |
XJ69 | Leu (L) | Glu (E) | Ile (I) | Thr (T) | Gln (Q) | Lys (K) | Ala (A) | Lys (K) |
P3 | Leu (L) | Glu (E) | Ile (I) | Thr (T) | Gln (Q) | Lys (K) | Ala (A) | Lys (K) |
HW | Leu (L) | Glu (E) | Ile (I) | Thr (T) | Gln (Q) | Lys (K) | Ala (A) | Lys (K) |
SA14 | Leu (L) | Glu (E) | Ile (I) | Thr (T) | Gln (Q) | Lys (K) | Ala (A) | Lys (K) |
SA14-14-2 | Phe (F) | Lys (K) | Val (V) | Ala (A) | His (H) | Met (M) | Val (V) | Arg (R) |