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Figure 5 | Virology Journal

Figure 5

From: Generation of a recombinant rabies Flury LEP virus carrying an additional G gene creates an improved seed virus for inactivated vaccine production

Figure 5

Pathogenicity of LEP and rLEP-G in adult mice. Six-week-old Balb/c mice were inoculated intracerebrally with LEP (A) or rLEP-G (B) in a 30 μl volume at doses of 100 to 103 FFU (black inverted triangle:100 FFU; black triangle: 101 FFU; black square: 102 FFU; black dot: 103 FFU). After infection, mice were observed for 21 days for clinical signs or death. The MLD50 of each virus was calculated by using the method of Reed and Muench.

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