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Figure 2 | Virology Journal

Figure 2

From: Sequence similarity between the erythrocyte binding domain 1 of the Plasmodium vivax Duffy binding protein and the V3 loop of HIV-1 strain MN reveals binding residues for the Duffy Antigen Receptor for Chemokines

Figure 2

Chemokine inhibition of PvRII binding to DARC+ erythrocytes. The erythrocyte rosette assay of Chitnis and Miller [6] was used to quantify chemokine inhibition of PvRII Binding to DARC+ Erythrocytes. Binding was determined by subtracting the number of COS-7 cells expressing pvRII with rosettes of chemokine-treated DARC+ human erythrocytes (per 20 fields at 200X magnification) from the number with rosettes of untreated erythrocytes, and dividing by the number with rosettes of untreated erythrocytes. The data shown are the mean of three separate experiments.

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Virology Journal

ISSN: 1743-422X