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Table 1 Neutralizing antibody responses against HTNV in mice 21 days after 1st vaccination

From: Fusion with extracellular domain of cytotoxic T-lymphocyte-associated-antigen 4 leads to enhancement of immunogenicity of Hantaan virus DNA vaccines in C57BL/6 mice

  

Titers for 50% neutralization

Vaccination groups

Mouse no.

Day 0

Day 21

CpG+pcDNA3/eCTLA4-S+M

1

< 8

16

 

2

< 8

32

 

3

< 8

32

 

4

< 8

16

 

5

< 8

16

pcDNA3/eCTLA4-S+M

1

< 8

16

 

2

< 8

16

 

3

< 8

16

 

4

< 8

16

 

5

< 8

32

CpG+pcDNA3/S+M

1

< 8

16

 

2

< 8

16

 

3

< 8

16

 

4

< 8

16

 

5

< 8

16

pcDNA3/S+M

1

< 8

16

 

2

< 8

16

 

3

< 8

16

 

4

< 8

8

 

5

< 8

8

pcDNA3

1

< 8

< 8

 

2

< 8

< 8

 

3

< 8

< 8

 

4

< 8

< 8

 

5

< 8

< 8

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Virology Journal

ISSN: 1743-422X