Distribution of sialic acid receptors and influenza A virus of avian and swine origin in experimentally infected pigs

Table 2 Results from immunohistochemical staining of influenza A virus antigen

Inoculum Necropsy day		AIV H4N6 PID4		AIV H4N6 PID8		SIV H1N2 PID4		SIV H1N1 PID4		Mock PID4		Mock PID8		Sent. PID8
Pig		A	B	C	D	E	F	G	H	I	J	K	L	M
	alv	+	+	-	+	-	+	+	-	-	-	-	-	-
lu1	br.iol	+*	+	-	+*	-	+	+	+	-	-	-	-	-
	bro	-	+*	-	-	+	+	+	+	-	-	-	-	-
	alv	+	+	+	+	+	+	+	+	-	-	-	-	-
lu2	br.iol	+*	+	-	+	+	+	+	+	-	-	-	-	-
	bro	-	+*	-	-	+	+	+	+	-	-	-	-	-
	alv	+	+	+	+	+	+	+	+	-	-	-	-	-
lu3	br.iol	+	+	+*	+*	+	+	+	+	-	-	-	-	-
	bro	+*	+*	-	-	+	+	+	+	-	-	-	-	-
	alv	+*	-	-	-	+	-	-	+	-	-	-	-	-
lu4	br.iol	-	-	-	-	+	+	+	+	-	-	-	-	-
	bro	-	-	-	-	+	+	+	+	-	-	-	-	-
	alv	-	+	+	+	+	-	-	+	-	-	-	-	-
lu5	br.iol	-	+	+	-	+	+	+	+	-	-	-	-	-
	bro	-	-	-	-	+	+	+	+	-	-	-	-	-
	alv	-	+	+	+	i	-	-	+	-	-	-	-	-
lu6	br.iol	-	+	-	-	i	+	+	+	-	-	-	-	-
	bro	-	+*	-	-	i	+	+	+	-	-	-	-	-
	alv	+	+	+	+	+	+	+	+	-	-	-	-	-
lu7	br.iol	-	+	+*	-	+	+	+	+	-	-	-	-	-
	bro	-	-	-	-	+	+	+	+	-	-	-	-	-
	alv	+	+	+	+	+	-	-	+	-	-	-	-	-
lu8	br.iol	-	+	+*	+*	+	-	+	+	-	-	-	-	-
	bro	+*	+*	-	-	+	+	+	+	-	-	-	-	-
	alv	-	-	-	+*	-	-	+	+	-	-	-	-	-
lu9	br.iol	-	-	-	-	+	+	+	+	-	-	-	-	-
	bro	-	-	-	-	+	+	+	+	-	-	-	-	-
Trachea		-	-	-	-	+	+	+	+	-	-	-	-	-
Nose		-	-	-	-	+	+	-	-	-	-	-	-	-

lu1: cranioventral part of the left cranial lobe; lu2: caudoventral part of the left cranial lobe; lu3: dorsal part of the left cranial lobe; lu4: ventral part of the right cranial lobe; lu5: middle part of the right cranial lobe; lu6: dorsal part of the right cranial lobe; lu7: middle part of the right middle lobe; lu8: middle part of the accessory lobe; and lu9: middle part of the right caudal lobe.
PID = post inoculation day, *Single positive cell demonstrated, i = not done.
Results from immunohistochemical staining of influenza A virus (infAv) antigens in nose, trachea and the nine lunge sections from avian influenza A virus (AIV) H4N6 inoculated pigs, swine influenza A virus (SIV) H1N1 and H1N2 inoculated pigs, the mock-inoculated pigs, and the sentinel (Sent.) pig which was contained in the AIV group. Each lung tissue section was evaluated for infAv antigens in alveoli (alv), bronchioles (br.iol), and bronchi (bro).

ISSN: 1743-422X