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Figure 3 | Virology Journal

Figure 3

From: Chikungunya triggers an autophagic process which promotes viral replication

Figure 3

Electron micrographs of CHIKV-infected HEK.293 cells. (A) Cells infected with ChikV at MOI = 5 were processed for electron microscopy. Infected cells presented an accumulation of membranous vesicles with clear content reminiscent of autophagosomes. A very large vesicle located near the nucleus (see enlargement in B) contained degradated material. Smooth reticulum surrounding the vacuole is indicated by arrows. The presence of bona fide viral particles with diameters of 40 nm and containing electron dense material detected inside this autophagosome are indicated in C.

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