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Figure 6 | Virology Journal

Figure 6

From: Heterologous prime-boost-boost immunisation of Chinese cynomolgus macaques using DNA and recombinant poxvirus vectors expressing HIV-1 virus-like particles

Figure 6

HIV-1 neutralisation assays. (A) Potency of IgG1b12 at neutralising lab-adapted isolate SF162, 1:5 IgG1b12 = 20 μg/mL; (B) potency of IgG1b12 at neutralising primary clade B isolate 91/US/005, 1:5 b12 = 20 μg/mL; Macaque serum collected at 3 time points: Solid black line = week 0; solid blue line = week 6; solid red line = week 9. Macaque 1057 seroneutralisation of primary isolates: (C) clade A isolate 92/UG/037; (D) clade D isolate 94/UG/114; (E) clade C isolate 97/ZA/003; (F) lab-adapted clade B isolate SF162; (G) human complement/macaque serum and clade C isolate 97/ZA/003; (H) heat inactivated human complement/macaque serum and clade C isolate 97/ZA/003. Data are presented as the mean of 3 tests ± SEM.

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