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Figure 4 | Virology Journal

Figure 4

From: Analysis of an ankyrin-like region in Epstein Barr Virus encoded (EBV) BZLF-1 (ZEBRA) protein: implications for interactions with NF-κB and p53

Figure 4

A schematic diagram of the ZEBRA protein illustrating the 3 functional domains of ZEBRA. ZEBRA domains 1 and 2 contain the transcriptional activation and DNA binding regions of the protein, respectively, and are similar to Fos/Jun transcription factors. Domain 3, the carboxyl region of ZEBRA denoted ZANK in this work, is required for both dimerization of the ZEBRA protein as well as interactions with NF-κB and p53 transcription factors.

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Virology Journal

ISSN: 1743-422X