Skip to main content

Table 2 Pathotyping and replication of the H10N8 virus in chickens§

From: Characterization of an H10N8 influenza virus isolated from Dongting lake wetland

Infection route Days of post infection Virus isolated from swabs No.of Survivors No.of Seroconverted Chickensb HI titers (Log2)
   Oropharyngeal Cloacal    
   No.of Chickens shedding virus Titera (log10 EID50/ml) No.of Chickens shedding virus Titera (log10 EID50/ml)    
Intravenous (8) 3 3 1.7 ± 0.3 4 3.1 ± 0.7 8 8 6.3 ± 0.5
  5 7 3.8 ± 0.6 4 3.0 ± 0.7    
  7 5 1.7 ± 0.5 3 1.6 ± 0.5    
Intranasal(8) 3 5 2.3 ± 0.8 4 2.0 ± 0.3 8 8 5.6 ± 1.2
  5 8 3.4 ± 1.1 7 3.3 ± 0.1    
  7 6 2.5 ± 0.9 5 1.3 ± 0.4    
  1. §One group of 8 six-week-old specific-pathogen-free white leghorn chickens were inoculated with 0.2 ml of 1:10diluted stock virus (106.3 EID50) intravenously and another group were inoculated with 106.0 EID50 of the virus in a 0.1 ml volume intranasally, and observed for 2 weeks after infection.
  2. a The mean titer in EID50/ml of swab media of the positive chickens.
  3. b Sera were harvested 3 weeks after infection, and seroconversion was confirmed by HI test.