Figure 1

Map of the BoHV-4 V.test strain genome and divergence with the 66-p-347 strain sequence. The LUR of both strains have been aligned. Genome features are represented in the upper part as grey and red oriented arrows. Red arrows represent genes with an in-frame STOP codon, an early Methionine or a high divergence level in the V.test strain compared to 66-p-347. Dark (resp. light) grey arrows represent genes with (resp. without) an evolutionarily conserved domain (see Methods). The exons of spliced genes are indicated under the given gene as thin light-blue lines. Percent divergence is shown as a black-filled curve, percent insertions and deletions are shown as a blue-filled curve. Percent G+C content is shown as a thin green curve, with the mean G+C content drawn as a thin horizontal green line. These percentages are measured in a 100 bp window sliding 3 bp. Repeat regions (R1, R2a, R2b) are depicted as hatched areas. The oriLyt region is mapped as a light-grey area within R2b and the conserved quasi-palindromic motif in the oriLyt region is indicated by a small vertical arrow.