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Figure 1 | Virology Journal

Figure 1

From: Latent HIV in primary T lymphocytes is unresponsive to histone deacetylase inhibitors

Figure 1

Effect of prostratin and HDAC inhibitors on HIV-latency. HIV-infected primary CD4 T cells cultured long-term on H80 (panel A) and ACH-2 cells (panel B) were treated with prostratin (500 nM), VPA (2 mM) and TSA (150 nM) for 18 hours and % increase in p24+ cells was determined by intracellular staining with HIV-core antibody (Coulter, USA) followed by flow cytometry as performed previously [11]. Mock indicates untreated control. One representative experiment out of 5 independent experiments with similar results is shown here.

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