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Table 4 Schematic overview of the experimental design.

From: Phenotypic characterization of patient dengue virus isolates in BALB/c mice differentiates dengue fever and dengue hemorrhagic fever from dengue shock syndrome

DENV-1 isolate DF DHF DSS NC
Titer PFU/mL 1.5 × 104 1.5 × 105 1.5 × 106 1.5 × 104 1.5 × 105 1.5 × 106 1.5 × 104 1.5 × 105 1.5 × 106 N.A
Day 3 p.i 3 3 3 3 3 3 3 3 3 9
Day 6 p.i 3 3 3 3 3 3 3 3 3 9
Day 15 p.i 3 3 3 3 3 3 3 3 3 9
Total no. of mice 27 27 27 18
  1. Mice were divided in groups of three depending on DENV-1 isolate for inoculation; titer of inoculum; and time of euthanasia. There were in total 99 mice included in the study, whereof 81 were inoculated with infectious DENV-1.
  2. N.A. = not applicable