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Figure 2 | Virology Journal

Figure 2

From: Japanese Encephalitis Virus wild strain infection suppresses dendritic cells maturation and function, and causes the expansion of regulatory T cells

Figure 2

Effects of P3 infection on DCs maturation. 1 × 105 freshly purified bmDCs were left mock-treated or treated with 1 MOI of P3 or UV-P3 with or without LPS (lipopolysacchide, Sigma-Aldrich, MO) for 3 days. The spDCs from mice, which have been challenged or immunized for 5 days, were obtained and treated with or without LPS. Expressions of CD40, CD80, CD83 and MHCI of the bmDCs (A,B) or spDCs (C,D) were evaluated by FACS. Relative fluorescence intensity to mock group (fold induction) was expressed as the means ± SD of triplicates. *, P < 0.05; **, P < 0.01.

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Virology Journal

ISSN: 1743-422X